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Vagus Nerve Stimulation: What It Is, How It Works, and Who It Helps

A patient-friendly guide to one of today’s most promising therapies


The vagus nerve is a communication superhighway linking your brain and body. When it struggles to regulate properly, symptoms like anxiety, poor digestion, or chronic stress can appear. One therapy that targets this nerve directly is called vagus nerve stimulation (VNS). For more knowledge about its role and anatomy, check out our full comprehensive vagus nerve article here.


But what is vagus nerve stimulation, how does it work, and who can benefit from it?


women doing alpha stim therapy on yoga mat

What Is Vagus Nerve Stimulation Therapy? (VNS Therapy)

Vagus nerve stimulation (VNS) uses controlled electrical signals to activate the vagus nerve. This therapy doesn’t rely on medication. Instead, it works by directly influencing the nervous system’s communication between the brain and body.

There are two main types:

  • Traditional (implanted) VNS – A surgical procedure where a device is implanted in the chest and wires connect to the vagus nerve. This is used for conditions such as epilepsy or treatment-resistant depression.

  • Non-invasive VNS – Methods like transcutaneous vagus nerve stimulation (tVNS) or RPSS therapy use external devices placed on the skin (often near the ear or neck). These stimulate vagal pathways without surgery, making them more accessible and safer for a broader range of patients.


(Learn more about the nerve itself in our Complete Guide to the Vagus Nerve.)


How Does Vagus Nerve Stimulation Work?

The vagus nerve carries signals in both directions — from the body to the brain and from the brain back to the organs. By stimulating this pathway, VNS can:

  • Increase parasympathetic activity (the “rest and digest” system).

  • Reduce overactive stress responses, helping the body recover more quickly.

  • Influence brain regions involved in mood and emotional balance, such as the amygdala and prefrontal cortex.

  • Support digestion and inflammation control by activating the body’s natural regulation systems.

Research has shown that VNS can help normalize nervous system activity in conditions like anxiety, depression, migraines, and digestive disorders.


Who Can Vagus Nerve Stimulation Help?

Vagus nerve stimulation has been studied across a wide range of conditions, many of which overlap with the struggles patients bring to our clinic. It may be helpful for people dealing with:

  • Chronic anxiety or depression – When lifestyle changes alone don’t provide enough relief, VNS can help regulate the brain circuits that drive mood and stress responses.

  • Migraines and chronic headaches – Research has shown that stimulating the vagus nerve can reduce the frequency and intensity of migraines by calming pain-processing pathways.

  • Digestive issues – Because the vagus nerve controls gut motility and secretions, stimulating it may help with conditions like IBS, bloating, or reflux.

  • Post-concussion symptoms – Patients who struggle with headaches, brain fog, or mood changes after a concussion may benefit from therapies that restore vagal tone.

  • Stress-related conditions – When the body stays stuck in fight-or-flight mode, non-invasive stimulation can provide the reset signal needed to restore balance.


While surgically implanted devices are used for severe cases (like epilepsy or treatment-resistant depression), non-invasive options such as RPSS and Alpha-Stim offer many of the same benefits without surgery. These therapies are safe, simple, and effective, and they’re used in clinics like ours to help patients reset their nervous systems more quickly.


If these symptoms sound familiar, vagus nerve stimulation could be part of the solution you’ve been looking for. Start by downloading our free Vagus Nerve Regulation Guide. It’s filled with simple, proven ways to support vagus nerve health at home.



When you’re ready, we can help you explore whether non-invasive therapies like RPSS or Alpha-Stim are the right next step for lasting balance and recovery. To discuss treatment options or schedule a consultation, contact us today.


Key Take-away:

Vagus nerve stimulation is not just a medical buzzword. It’s a therapy that targets the body’s most important regulation pathway. VNS Therapy can help people with anxiety, migraines, digestive issues, and stress-related conditions find relief when self-care alone isn’t enough. Whether through implanted devices in severe cases or non-invasive methods like RPSS and Alpha-Stim, VNS gives the nervous system the input it needs to reset.

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